ASSOCIATION OF HYPERHOMOCYSTINEMIA WITH ACUTE MYOCARDIAL INFARCTION IN YOUNG PATIENTS

Abstract

The relative risk of developing coronary artery disease (CAD) in Pakistani population is highest in early ages. The pathogenesis of arterial thrombotic disease involves multiple genetic and environmental factors related to atherosclerosis and thrombosis. Homocysteine is a simple amino acid that has recently received a great deal of attention as a risk factor for atherothrombotic vascular disease. Hence hyperhomocystinemia, a thrombotic marker which is being classified as a proximate risk factor, may act synergistically with other classical risk factors to accentuate the risk of CAD in young population.