FREQUENCY OF SIGNIFICANT THREE VESSEL CORONARY ARTERY DISEASE IN NON ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION HAVING LOW HIGH DENSITY LIPOPROTEIN LEVEL

Abstract

Objective: To calculate the frequency of significant three-vessel coronary artery disease in patients presenting with Non ST- segment elevation myocardial infarction having low high density lipoprotein levels. Methodology: This study was conducted at emergency department, Ch Pervaiz Elahi Institute of Cardiology, Multan from February 2010 to August 2010. One hundred and twenty six patients with non ST-segment elevation myocardial infarction having low HDL level admitted, and scheduled for coronary angiography. Demographic data was noted. The data was analyzed by using software SPSS (Version 14.0). Results: Mean age of pts was 53.25 ± 9 yrs. 79(63%) were male and 47(37%) female patients. The incidence of significant three vessel coronary artery disease in the study population was 27(21.4%). Out of 79 male patients 19(25%) showed significant three vessel disease and in 60 (75%) patients there was no significant disease. Similarly out of 47 female patients 8(17%) showed disease while in 39(83%) it was absent. The occurrence of significant three vessel disease was more in male and in younger age group. Conclusion: It was concluded that lower HDL levels are significant predictor of severity of coronary artery disease and are associated with significant three vessel disease.