ENERGY CALCULATIONS OF A SALT OF SYNTHETIC NEUROTRANSMITTER (ACETYLCHOLINE CHLORIDE) OXIDATION BY CHLRAMINE- T (A DISINFECTANT)

Abstract

Acetylcholinestrase inhibitors can have a negative effect on cardiac output. So we have tried to mimic the action of acetylcholinesterase by in vitro degradation of acetylcholine chloride. The activation parameters the energy of activation, enthalpy, Entropy and free energy contents (E" !l H, !l S~, !lO') of the breakdown (oxidation) of acetylcholine chloride by Cholramine-T were calculated at temperature range from 30° C to 60" C. The reaction medium was kept constant.