Captopril In The Management of Heart Failure

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Pakistan Cardiac Society

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MATERIAL & METHODS: Criteria for Selection: 1. Patients with correctable cardiac disease but in refractory stage (e.g. inoperable chronic rheumatic heart disease, coronary artery disease). 2. Patients with incorrectable cardiac disease e.g. cárdiomyopathy. 3. Lschemic cardiac patients with associated incurable disease e.g. corpulmonale with Lschemic heart disease and liver disease. DISCUSSION: For the management of refractory cardiac failures, who do not respond adequately to the conventional therapy of digoxin and diuretics, new therapeutic modalities have now become available.It consists of control of venous return by decreasing “the preload” through the use of nitrates, or reduction of after load by hydrallazine which acts by peripheral arterial vasodilation.This series consisted of only of patient suffering from cardiac failures, and the dose of the drug required by them was much less than that which usual causes side effects.

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Pakistan Heart Journal; Vol. 17 No. 4 (1984)

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