Procedural and Short-Term Outcomes of Patent Ductus Arteriosus Stenting in Patients with Duct-Dependent Congenital Heart Disease

Abstract

Objectives: To evaluate procedural success, early clinical outcomes, complications, stent patency, pulmonary artery growth, and progression to surgical intervention following PDA stenting in neonates and young infants with duct-dependent congenital heart disease. Methodology: This was an observational cohort study with retrospective data collection and prospective clinical follow-up. This was an observational cohort study with retrospective data collection and prospective clinical follow-up for up to 12 months. Thirty patients with duct-dependent congenital heart disease underwent percutaneous PDA stenting at a single tertiary pediatric cardiac center. Baseline demographic, diagnostic, and procedural data were obtained from institutional medical records, while follow-up outcomes were assessed prospectively for up to 12 months. Evaluated variables included procedural success, oxygen saturation, hemodynamic stability, complications, pulmonary artery growth, surgical progression, and survival. Results: Successful stent deployment was achieved in all 30 infants. Post-procedural systemic oxygen saturation improved to 75–90%, with all patients achieving oxygen saturation greater than 80%. Most infants achieved early hemodynamic stability and required short intensive care unit stays. No early procedural complications or re-interventions were observed. One late stent thrombosis occurred during follow-up. Adequate pulmonary artery growth was observed in the majority of infants with available imaging. At 12 months, most patients had progressed to definitive or palliative surgical intervention, and overall survival was high. Conclusion: PDA stenting appears to be a feasible and effective palliative strategy in selected neonates with duct-dependent congenital heart disease, demonstrating high procedural success, early clinical stabilization, and acceptable short-term outcomes. Larger multicenter studies are needed to further define its role relative to surgical palliation.