FREQUENCY OF AUTONOMIC CARDIOVASCULAR DYSFUNCTION IN PATIENTS WITH DECOMPENSATED CHRONIC LIVER DISEASE

Abstract

Objective: To determine the frequency of autonomic cardiovascular dysfunction in patents with decompensated cirrhosis. Methodology: This cross-sectional study was conducted from august 2018 to January 2019 at department of medicine, Abbassi Shaheed hospital. A total of 187 diagnosed patients of decompensated chronic liver disease were consecutively included. Lying and standing BP were taken for orthostatic hypotension while 1 minute ECG was recorded for decrease in HRV during breathing. Results: Out of 187, 72.7% had autonomic cardiovascular dysfunction. Conclusion: Almost two thirds of cirrhotic were found to have hemodynamic alterations. Treatment is largely supportive and empiric. Further studies are needed to recognize the burden of autonomic dysfunction.