COMPARISON OF CORONARY ARTERY DIAMETER AMONG PATIENTS WITH AND WITHOUT DIABETES MELLITUS

Abstract

Objective: To compare the coronary arteries diameter between diabetic and nondiabetic patients undergoing coronary angiography. Methodology: This cross sectional comparative study was carried out in cardiac catheterization laboratory, from January to June 2010. Patients were divided into two groups; diabetics and nondiabetics. Coronary angiography was performed and quantitative analysis of coronary segments was performed. Results: A total of 278 patients, 139 in each group were included in the study. Mean age±SD (years) in diabetic and nondiabetic groups was 52.8±7.531 V 52.9±6.79; P=0.91 respectively. Hypertension among diabetics and non diabetics were66(47%)V 59(42.4%) P=0.39 respectively. Left main stem coronary artery (LMS) in diabetics and non diabetics were 4 V 4.18 P=0.008 respectively. Proximal segments of left anterior descending (LAD) coronary artery sizes in diabetics and non-diabetics were 2.99 V 3.1P =0.000 while mid and distal segments were 2.95 V 3.14 P=0.000 and 1.95 V 2.42 P=0.000 respectively. Sizes of various segments of proximal left Circumflex (LCx) coronary artery in diabetics and non-diabetics were 2.99 V 3.0 P=0.37 while distal circ 1.85 V 2.29 P=0.000 respectively. Proximal segments of right coronary artery in diabetic and nondiabetic group were 3.02±0.25mmV 3.18±0.25mm; P=0.000 while mid and distal segments were 2.99±0.26V 3.18±0.25; P=0.000 and 2.43±0.51V2.87±0.32; P=0.000 respectively. Conclusion: In this study, coronary arteries in diabetic patients were found to be narrower than in Non diabetic subjects. The right coronary artery , left main stem, left anterior descending and distal circumflex arteries were more significantly affected in diabetics and proximal circumflex was not significantly affected.