DIAGNOSTIC ACCURACY OF COMPUTED TOMOGRAPHIC ANGIOGRAPHY FOR THE DETECTION OF STENOTIC LESIONS OF THE DISTAL SEGMENTS OF MAIN CORONARY ARTERIES

Abstract

Objective: It was to find out the diagnostic accuracy of CT angiography for the detection of stenotic atherosclerotic lesions in the distal segments of 4 main coronary arteries using invasive angiography as gold standard. Methodology: This observational study was carried out at Department of Cardiology, Hayatabad Medical Complex, Peshawar. It included 50 patients from June to September 2011. CT and invasive angiography was performed for each patient and data was analyzed in SPSS software version 10.0 to analyze the findings of distal segments of the 4 main arteries. Results: The sensitivity for detection of stenotic atherosclerotic lesions in left main stem, left anterior descending, circumflex and right coronary arteries was 87.5%, 100%, 66.67% and 50% respectively. Specificity for detection of stenotic atherosclerotic lesions in left main stem, left anterior descending, circumflex and right coronary artery was 100% for all. Positive predictive value for detection of stenotic atherosclerotic lesions in left main stem, left anterior descending, circumflex and right coronary arteries was also 100% for all and negative predictive value was 97.6%, 100%, 97.91% and 95.83% for the left main stem, left anterior descending, circumflex and right coronary arteries respectively. Conclusion: Invasive angiography is more sensitive than CT angiography but has equal specificity to invasive angiography for the detection of stenotic lesions in the distal segments of 4 main coronary arteries.