PATTERN OF CORONARY ATHEROSCLEROSIS IN SMOKERS AND NON-SMOKERS

Abstract

OBJECTIVE: The study was carried out to determine the pattern of coronary atherosclerosis among smokers and nonsmokers. METHODS: The study was carried out in LNH; angiograms of smokers and non-smokers were reviewed and recorded on Performa. Variables were displayed as percentages, compared by chi square test. R-R and CI were also obtained fo different variables. RESULTS: A total of 400 patients were enrolled, 184 were smokers and 216 were non-smokers. There were 83% male smokers and 73% males in non-smoking group. Hypertension was seen in 43%, DM was seen in 31% and Dyslipidemia was seen in 28% of smokers. Among smokers 71% had lesions in LAD (p-0.002), 56% in Cx (p- 0.001) and 59% in RCA (p-0.013). 18% of smokers had single vessel disease, 26% had two-vessel disease and 42% had triple vessel disease (p-0.04). CABG was done in 37% and 24% were managed by PTCA. Among non-smokers 53% had hypertension, 32% had DM and 33% found to have dyslipidemia. LAD was involved in 59%, Cx in 37% and RCA was involed in 46% of non-smokers. Triple vessel disease was seen in only 29% and CABG was performed in 26% of non-smokers. CONCLUSION: Smokers tend to have significantly high multi-vessel disease with lower incidence of known predisposing risk factors for atherosolerosis. LAD was more commonly affected in smokers and more of our CAD patients who smoke underwent CABG.