LOW HDL LEVELS AS A MAJOR RISK FACTOR IN PATIENTS OF ACUTE MYOCARDIAL INFARCTION

Abstract

Objective: To determine the frequency of low HDL levels in patients presentingwith acute myocardial infarction. Methodology: It was a descriptive cross-sectional study. Conducted from 1stJanuary to 31st July 2016. Patients with acute myocardial infarction admitted atEmergency Department of Chaudary Pervaiz Elahi Institute of cardiology wereincluded in the study via non-probability purposive sampling. All patients of eithergender between 20 to 60 years of age were included. Permission was taken fromthe ethical committee of the hospital. Informed consent was taken from all thepatients included in the study. Twelve hours fasting lipid profile of the patientswere taken and HDL levels were noted. Statistical analysis was performed byentering all the data in SPSS version 16.0. Results: There were 382 patients in total. Mean age of the patients was 54.05+7.39 years. There were 218 (57.1%) males. Mean level of HDL cholesterol wasfound to be 41.03+8.96mg/dl ranging fromaminimumof 24mg/dl to 63mg/dl.Isolated low level of HDL cholesterol was found to be present in 84 (22%) while itwas not present in 298 (78%) of the patients. There was no significant effect ofage, gender and smoking noted on the frequency of isolated low HDL. Conclusion: Low HDL level is noted to be present in a high percentage of acute MIpatients and can be a major risk contributor. Key Words: Dyslipidemia, Isolated low HDL .